He starred as Rocco Bezauri in the TV series Rebelde from 2005 to 2006. From 2010 to 2011 he had a recurring role as Alex Santiago in the series Pretty Little Liars. He also starred as Javier Luna in the TV series 90210 from 2010 to 2011. From 2012 to 2013 he starred as Miles in the television series Underemployed. Diego starred as Tyler Adams in the 2011 TV movie Mean Girls 2 and as Drew Boley in the 2012 movie Rock of Ages. He is scheduled to appear in the upcoming films Summer Camp, Eden, Another You, City of Dead Men, and Pele. For Rock of Ages he won Favorite Movie Actor at the 2012 ALMA Awards.